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HA-100 (hydrochloride)

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HA-100 (hydrochloride) Suppliers list
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:HA-100 (hydrochloride)
CAS:210297-47-5
Purity:99%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:HA-100 dihydrochloride
CAS:210297-47-5
Purity:98% Package:$240.9/5mg;$446.9/10mg;$1029.9/25mg;$1957.9/50mg;$3089.9/100mg;Bulk package Remarks:98%
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 17754423994 17754423994
Email: 2853530910@QQ.com
Products Intro: Product Name:HA-100 dihydrochloride
CAS:210297-47-5
Purity:98% HPLC LCMS Package:100mg;500mg;1g
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 21-31433387 15618786686
Email: sales@rechemscience.com
Products Intro: CAS:210297-47-5
Purity:98% Package:1g;5g
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
Products Intro: Product Name:HA-100 hydrochloride
CAS:210297-47-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
HA-100 (hydrochloride) Basic information
Product Name:HA-100 (hydrochloride)
Synonyms:5-piperazin-1-ylsulfonylisoquinoline:dihydrochloride;HA-100 dihydrochloride DISCONTINUED, Offer I891000
CAS:210297-47-5
MF:C13H16ClN3O2S
MW:313.8
EINECS:
Product Categories:
Mol File:210297-47-5.mol
HA-100 (hydrochloride) Structure
HA-100 (hydrochloride) Chemical Properties
storage temp. Store at -20°C
solubility insoluble in EtOH; ≥131.8 mg/mL in H2O; ≥19.17 mg/mL in DMSO with ultrasonic
form A crystalline solid
Safety Information
MSDS Information
HA-100 (hydrochloride) Usage And Synthesis
DescriptionHA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50s = 8, 12, and 4 μM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC50 = 240 μM).
UsesHA-100 dihydrochloride is an inhibitor of MYLK, PKA, and PKC.
references[1] hagiwara m, inagaki m, watanabe m, et al. selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives[j]. molecular pharmacology, 1987, 32(1): 7-12.
[2] krebs e g. protein kinases[j]. current topics in cellular regulation, 1972, 5: 99-133.
HA-100 (hydrochloride) Preparation Products And Raw materials
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