| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:MitoP
CAS:74597-01-6
Purity:95% Package:5mg;10mg;50mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:MitoP
CAS:74597-01-6
Purity:详情请点击官网 Package:1 mg
|
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| Product Name: | MitoP | | Synonyms: | MitoP;(3-hydroxyphenyl)methyl]triphenyl-phosphonium,monobromide | | CAS: | 74597-01-6 | | MF: | C25H22BrOP | | MW: | 449.33 | | EINECS: | | | Product Categories: | | | Mol File: | 74597-01-6.mol |  |
| | MitoP Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 20 mg/mL; DMSO: 20 mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL; Ethanol: 12 mg/mL | | form | A crystalline solid |
| | MitoP Usage And Synthesis |
| Description | MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP.1,2 Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration. | | References | 1. Cochemé, H.M., Quin, C., McQuaker, S.J., et al. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix Cell Metab. 13(3),340-350(2011).
2. Cochemé, H.M., Logan, A., Prime, T.A., et al. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila Nat. Protoc. 7(5),946-958(2012). |
| | MitoP Preparation Products And Raw materials |
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