| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 17702719238 |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:RSM932A
CAS:850807-63-5
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| Company Name: |
Zhengzhou Alfachem Co., Ltd.
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| Tel: |
0371-53765687 18937137882 |
| Email: |
2853979813@qq.com |
| Products Intro: |
Product Name:1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide
CAS:850807-63-5
Purity:0.98 Package:25mg;100mg;250mg;500mg;1g;5g
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| Company Name: |
Shanghai Rechem science Co., Ltd.
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| Tel: |
21-31433387 15618786686 |
| Email: |
sales@rechemscience.com |
| Products Intro: |
Product Name:RSM932A
CAS:850807-63-5
Purity:98% Package:1g/
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| | RSM932A Basic information |
| Product Name: | RSM932A | | Synonyms: | RSM932A;RSM-932A; RSM 932A; RSM932A; TCD 717; TCD717; TCD-717.;TCD 717;TCD717;TCD-717.;1,1''-([1,1''-Biphenyl]-4,4''-diylbis(methylene))bis(4-(methyl(p-tolyl)amino)quinolin-1-ium) bromide;1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide;1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide | | CAS: | 850807-63-5 | | MF: | C46H38BrCl2N4+ | | MW: | 797.64 | | EINECS: | | | Product Categories: | | | Mol File: | 850807-63-5.mol |  |
| | RSM932A Chemical Properties |
| Melting point | 255-257 °C | | storage temp. | Store at -20°C | | solubility | DMSO: 3 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml | | form | A crystalline solid | | color | White to yellow |
| | RSM932A Usage And Synthesis |
| Description | RSM-932A is a selective inhibitor of choline kinase α (CHOKα; IC50s = 1 and >50 μM for CHOKα and β, respectively). It induces apoptosis via CHOP signaling and endoplasmic reticulum (ER) stress in MDA-MB-231, MCF-7, SW620, and H460 cancer cells, but it only induces cell cycle arrest and not apoptosis in NCM460 and MCF-10A normal epithelial cells. RSM-932A inhibits the growth of HT-29 colon cancer cells in vitro (IC50 = 1.15 μM) and in vivo in a mouse xenograft model (ED50 = 7.5 mg/kg). |
| | RSM932A Preparation Products And Raw materials |
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