Alverine manufacturers
- alverine
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- $1.00 / 1KG
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2020-01-10
- CAS:150-59-4
- Min. Order: 1KG
- Purity: 98% HPLC
- Supply Ability: 10 tons/month
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| Alverine Basic information |
Product Name: | Alverine | Synonyms: | n-ethyl-n-(3-phenylpropyl)benzenepropanamine;SESTRON;Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-;di(phenylpropyl)ethylamine;dipropylin;n-ethyl-3,3’-diphenyl-dipropylamin;n-ethyl-3,3’-diphenyldipropylamine;N-Ethyl-3,3'-diphenyldipropylamine | CAS: | 150-59-4 | MF: | C20H27N | MW: | 281.44 | EINECS: | 205-763-5 | Product Categories: | | Mol File: | 150-59-4.mol | ![Alverine Structure](CAS/GIF/150-59-4.gif) |
| Alverine Chemical Properties |
Hazardous Substances Data | 150-59-4(Hazardous Substances Data) | Toxicity | women,TDLo,oral,126mg/kg/5W-I (126mg/kg),BEHAVIORAL: ANOREXIA (HUMANLIVER: LIVER FUNCTION TESTS IMPAIREDLIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE",Journal of Hepathology. Vol. 27, Pg. 399, 1997. |
| Alverine Usage And Synthesis |
Originator | Alverine citrate,Kemikos | Uses | Anticholinergic. | Definition | ChEBI: A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel synd
ome. | Manufacturing Process | 2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium
hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt
as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was
obtained.
In practice it is usually used as citrate. | Therapeutic Function | Anticholinergic, Spasmolytic |
| Alverine Preparation Products And Raw materials |
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