| Company Name: |
MedChemexpress LLC
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| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:EF-5
CAS:152721-37-4
Purity:200RMB/1mg Package:>98%
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| Company Name: |
Zhengzhou HSH Science & Technology Co., Ltd.
|
| Tel: |
0371-55932928 18937192232 |
| Email: |
1282296214@qq.com |
| Products Intro: |
Product Name:2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)acetamide
CAS:152721-37-4
Purity:0.98 Package:5mg;10mg;100mg;250mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;1kg;大量
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EF-5 manufacturers
- EF-5
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- $43.00 / 5mg
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2024-11-19
- CAS:152721-37-4
- Min. Order:
- Purity: 98.26%
- Supply Ability: 10g
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| Product Name: | EF-5 | | Synonyms: | EF-5;1H-Imidazole-1-acetamide, 2-nitro-N-(2,2,3,3,3-pentafluoropropyl)-;EF5 >=98% (HPLC);inhibit,EF 5,EF-5,Inhibitor;EF-5, 10 mM in DMSO | | CAS: | 152721-37-4 | | MF: | C8H7F5N4O3 | | MW: | 302.16 | | EINECS: | | | Product Categories: | | | Mol File: | 152721-37-4.mol |  |
| density | 1.66±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (413.69 mM) | | form | Solid | | pka | 12.32±0.46(Predicted) | | color | White to off-white |
| Biological Activity | EF5 is a 2-nitroimidazole-based hypoxia marker corresponding to a pentafluorinated derivative of the hypoxic cell-radiation sensitizer etanidazole. Under low oxygen (hypoxic) condition, reductive activation of its 2-nitroimidazole moiety leads to enhanced EF5 adduct formation with protein thiols and reduced glutathione. The pentafluorination derivatization substantially decreases the proportion of low molecular weight hydrolytic fragmentation of the adducts, making EF5 superior to etanidazole when utilized as a hypoxia marker by immunohistological staining. |
| | EF-5 Preparation Products And Raw materials |
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