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ChemPep, Inc.
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Products Intro: |
Product Name:mPEG4-Hydrazide CAS:1449390-65-1 Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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mPEG4-Hydrazide manufacturers
- m-PEG5-Hydrazide
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- $0.00 / 250mg
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2024-03-27
- CAS:1449390-65-1
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
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| mPEG4-Hydrazide Basic information |
| mPEG4-Hydrazide Chemical Properties |
Boiling point | 443.9±40.0 °C(Predicted) | density | 1.098±0.06 g/cm3(Predicted) | pka | 12.82±0.35(Predicted) |
| mPEG4-Hydrazide Usage And Synthesis |
Biological Activity | m-PEG5-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| mPEG4-Hydrazide Preparation Products And Raw materials |
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Tag:mPEG4-Hydrazide(1449390-65-1)
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