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ChemStrong Scientific Co.,Ltd
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Product Name:Travoprost Impurity 22
CAS:62145-07-7
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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BOC Sciences
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Product Name:11-Keto fluprostenol
CAS:62145-07-7
Purity:98% Package:1G;10G;100G Remarks:11-Keto fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency.
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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:11-keto Fluprostenol
CAS:62145-07-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| | 11-KETO FLUPROSTENOL Basic information |
| Product Name: | 11-KETO FLUPROSTENOL | | Synonyms: | FLUPROSTENOL PROSTAGLANDIN D2;11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;Travoprost Impurity 17（11-keto Fluprostenol）;Travoprost Impurity 22;5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)-;11-KETO FLUPROSTENOL | | CAS: | 62145-07-7 | | MF: | C23H27F3O6 | | MW: | 456.45 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 11-KETO FLUPROSTENOL Chemical Properties |
| Boiling point | 627.3±55.0 °C(Predicted) | | density | 1.331±0.06 g/cm3(Predicted) | | solubility | PBS (7.2): 29 mg/ml | | pka | 4.76±0.10(Predicted) |
| | 11-KETO FLUPROSTENOL Usage And Synthesis |
| Description | 11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.1 Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.2 | | Definition | ChEBI: 11-keto Fluprostenol is a prostanoid. | | References | 1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α Nature 250(464),330-331(1974).
2. Monneret, G., Cossette, C., Gravel, S., et al. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils J. Pharmacol. Exp. Ther. 304(1),349-355(2003). |
| | 11-KETO FLUPROSTENOL Preparation Products And Raw materials |
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