| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:PC-Biotin-PEG4-NHS-carbonate
CAS:2055198-03-1
Purity:96% HPLC Package:10MG;25MG;50MG;100MG;1G;5G
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PC-Biotin-PEG4-NHS carbonate manufacturers
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| | PC-Biotin-PEG4-NHS carbonate Basic information |
| Product Name: | PC-Biotin-PEG4-NHS carbonate | | Synonyms: | PC-Biotin-PEG4-NHS carbonate;Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-[23-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl ester | | CAS: | 2055198-03-1 | | MF: | C35H50N6O14S | | MW: | 810.87 | | EINECS: | | | Product Categories: | | | Mol File: | 2055198-03-1.mol |  |
| | PC-Biotin-PEG4-NHS carbonate Chemical Properties |
| density | 1.39±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 13.90±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | PC-Biotin-PEG4-NHS carbonate Usage And Synthesis |
| Description | PC-Biotin-PEG4-NHS carbonate is a unique amine reactive, photocleavable biotin reagent that is useful for introducing a biotin moiety to amine-containing biomolecules. The NHS carbonate portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). | | Uses | PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | PC-Biotin-PEG4-NHS carbonate Preparation Products And Raw materials |
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