| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:PSB-12379
CAS:1802226-78-3
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | PSB-12379 Basic information |
| Product Name: | PSB-12379 | | Synonyms: | PSB-12379;Adenosine, N-(phenylmethyl)-, 5'-[hydrogen P-(phosphonomethyl)phosphonate];PSB 12379,PSB12379 | | CAS: | 1802226-78-3 | | MF: | C18H23N5O9P2 | | MW: | 515.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1802226-78-3.mol |  |
| | PSB-12379 Chemical Properties |
| Boiling point | 894.2±75.0 °C(Predicted) | | density | 1.89±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Water: 5 mg/ml, sonicated | | form | A solid | | pka | 1.62±0.10(Predicted) | | color | White to off-white |
| | PSB-12379 Usage And Synthesis |
| Description | PSB-12379 is an inhibitor of ecto-5’-nucleotidase (CD73; Kis = 2.21 and 9.03 nM for the recombinant human and rat enzyme, respectively). It is selective for CD73 over human nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), -2, and -3, ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1), -2, and -3 (Kis = >10,000 nM for all), as well as the purinergic P2Y1 and P2Y12 receptors at 10 μM. PSB-12379 inhibits CD73 in isolated human serum with a Ki value of 18.8 nM. |
| | PSB-12379 Preparation Products And Raw materials |
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