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ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate

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ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MMG-11
CAS:313254-94-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:MMG-11
CAS:313254-94-3
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:MMG 11
CAS:313254-94-3
Purity:>=97%(HPLC) Package:$184.9/5mg;$307.9/10mg;$693.9/25mg;$1197.9/50mg;$1963.9/100mg;Bulk package Remarks:97%(HPLC)
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:MMG-11
CAS:313254-94-3
Package:2mg;58USD
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Products Intro: Product Name:MMG-11
CAS:313254-94-3
Purity:98% Package:1g;10g;100g

ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate manufacturers

  • MMG-11
  • MMG-11 pictures
  • $58.00 / 2mg
  • 2024-10-24
  • CAS:313254-94-3
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Basic information
Product Name:ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
Synonyms:ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate;MMG-11;MMG 11,MMG11;2-Furancarboxylic acid, 5-[2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl]-, ethyl ester
CAS:313254-94-3
MF:C15H14O7
MW:306.26746
EINECS:
Product Categories:
Mol File:313254-94-3.mol
ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Structure
ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Chemical Properties
Boiling point 565.6±50.0 °C(Predicted)
density 1.430±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (326.51 mM; Need ultrasonic)
form Solid
pka7.05±0.40(Predicted)
color Light yellow to brown
Safety Information
MSDS Information
ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Usage And Synthesis
Biological ActivityMMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 μM for Pam3CSK4-induced hTLR2/1 and 5.7 μM for Pam2CSK4-induced hTLR2/6 responses[1]. MMG-11 neither shows cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β or TNF. MMG-11 (0.01-100 μM) shows no cytotoxic effects up to 100 μM in peripheral blood mononuclear cells (PBMCs)[1].
storageStore at -20°C
References[1]. Grabowski M, et al. Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening. Biochem Pharmacol. 2018 Aug;154:148-160.
ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate Preparation Products And Raw materials
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