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MGV354

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MGV354 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:(Rac)-MGV354
CAS:1852495-86-3
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:(Rac)-MGV354；MGV354
CAS:1852495-86-3
Purity:98.00% Package:1 mg；10 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:MGV354
CAS:1852495-86-3
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:MGV354
CAS:1852495-86-3
Purity:98% HPLC Package:10mg，500mg，1g，5g，10g，more
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:MGV354
CAS:1852495-86-3
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
MGV354 Basic information
Product Name:MGV354
Synonyms:MGV354;(Rac)-MGV354;pressure,drop,intraocular,Guanylate Cyclase,(Rac)MGV354,Inhibitor,activator,topical,(Rac) MGV354,inhibit,sGC,(Rac)-MGV354,(Rac)-MGV-354,ocular;MGV354|MGV 354
CAS:1852495-86-3
MF:C35H37N5O3
MW:575.71
EINECS:
Product Categories:
Mol File:1852495-86-3.mol
MGV354 Structure
MGV354 Chemical Properties
Boiling point 824.8±65.0 °C(Predicted)
density 1.36±0.1 g/cm3(Predicted)
solubility DMSO : 100 mg/mL (173.70 mM; Need ultrasonic)
pka3.20±0.25(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
MGV354 Usage And Synthesis
Biological Activity(Rac)-MGV354 is the racemate of MGV354. MGV354 is a soluble guanylate cyclase (sGC) activator with EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively[1].
References[1]. Ehara T, et al. The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. J Med Chem. 2018 Mar 22;61(6):2552-2570.
MGV354 Preparation Products And Raw materials
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