| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal
Purity:monoclonal HDAC4-144, purified from hybridoma cell culture Package:200μL Remarks:H0163
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| Company Name: |
AmyJet Scientific Inc
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| Tel: |
+86-027-59626688 |
| Email: |
marking@amyjet.com |
| Products Intro: |
Product Name:Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal
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| | Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal Basic information |
| | Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal Usage And Synthesis |
| Uses | Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal has been used in:
- enzyme linked immunosorbent assay (ELISA)
- immunoblotting
- immunocytochemistry
- immunoprecipitation
| | General Description | Monoclonal Anti-Histone Deacetylase 4 (HDAC4) (mouse IgG2a isotype) is derived from the HDAC4-144 hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to amino acids of human HDAC4 with C-terminal added lysine, conjugated to KLH. HDAC4 belongs to the class II of Mammalian HDACs. | | Biochem/physiol Actions | Histone deacetylase (HDAC) catalyzes the deacetylation of histones. HDAC4 is implicated in transcriptional repression. It dynamically migrates between nucleus and cytoplasm through its nuclear import and export signals. Interaction of HDAC4 with 14-3-3 and myocyte enhancer factor-2 (Mef2) proteins disturbs such shuttling and thus directs HDAC4 to the cytoplasm and the nucleus, respectively. |
| | Anti-Histone Deacetylase 4 (HDAC4) antibody, Mouse monoclonal Preparation Products And Raw materials |
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