NEBRACETAM HYDROCHLORIDE
| 中文名称 | NEBRACETAM HYDROCHLORIDE |
|---|---|
| 中文同义词 | 化合物NEBRACETAM HYDROCHLORIDE;4-(氨基甲基)-1-苄基吡咯烷-2-酮盐酸盐 |
| 英文名称 | 4-(aminomethyl)-1-benzylpyrrolidin-2-one hydrochloride |
| 英文同义词 | 4-(aminomethyl)-1-benzylpyrrolidin-2-one hydrochloride;Nebracetam hydrochloride;WEB 1881 FU hydrochloride;Alzheimer's,Inhibitor,mAChR,Ca2+,inhibit,Nebracetam hydrochloride,Muscarinic acetylcholine receptor,2-DG,Nebracetam,2-deoxyglucose,WEB 1881 FU |
| CAS号 | 1177279-49-0 |
| 分子式 | C12H17ClN2O |
| 分子量 | 240.73 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1177279-49-0.mol |
| 结构式 |  |
NEBRACETAM HYDROCHLORIDE 性质
| 储存条件 | Store at -20°C, protect from light, sealed storage, away from moisture |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
Nebracetam hydrochloride 是 M1 毒蕈碱的激动剂，会引起胞内 Ca2+ 浓度升高。其 EC50 值为1.59 mM。
Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms.
| Animal Model: | Male Wistar rats weighing 200-250 g. |
| Dosage: | 10, 20 mg/kg. |
| Administration: | P.O. (single dose). |
| Result: | Able to correct this scopolamine-induced disruption of spatial cognition. |
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/11/08 | HY-113970A | NEBRACETAM HYDROCHLORIDE Nebracetam hydrochloride | 1177279-49-0 | 5mg | 850元 |
| 2024/11/08 | HY-113970A | NEBRACETAM HYDROCHLORIDE Nebracetam hydrochloride | 1177279-49-0 | 10mM * 1mLin DMSO | 935元 |