- BI-3812
-
- $112.00 / 1mg
-
2024-11-19
- CAS:2166387-64-8
- Min. Order:
- Purity: 99.79%
- Supply Ability: 10g
- BI-3812
-
- $112.00 / 1mg
-
2024-11-19
- CAS:2166387-64-8
- Min. Order:
- Purity: 99.79%
- Supply Ability: 10g
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| | BI-3812 Basic information |
| Product Name: | BI-3812 | | Synonyms: | BI3812;BI 3812;BI-3812;CPD1815;1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide;4-Piperidinecarboxamide, 1-[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]-N,N-dimethyl-;BI-3812/CPD1815;BI 3812,BI3812,BI-3812,Inhibitor,inhibit,Bcl-2 Family | | CAS: | 2166387-64-8 | | MF: | C26H32ClN7O5 | | MW: | 558.03 | | EINECS: | | | Product Categories: | APIs | | Mol File: | 2166387-64-8.mol |  |
| | BI-3812 Chemical Properties |
| density | 1.40±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:22.92(Max Conc. mg/mL);41.07(Max Conc. mM) | | form | Solid | | pka | 14.73±0.46(Predicted) | | color | Off-white to pink |
| | BI-3812 Usage And Synthesis |
| Biological Activity | BI-3812 is a potent BCL6 inhibitor with IC50 less than 3 nM. | | in vivo | BI-3812 is a BCL6 inhibitor, with an IC 50 of ≤3 nM. BI-3812 shows an IC 50 of 40 nM for the cellular BCL6. | | target | | Target | Value | BCL6
(Cell-free assay) | 3 nM |
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| | BI-3812 Preparation Products And Raw materials |
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