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Product Name:Myceliothermophin E
CAS:955083-90-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Product Name:Myceliothermophin E
CAS:955083-90-6
Purity:70% Package:1mg
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TargetMol Chemicals Inc.
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Product Name:Myceliothermophin E
CAS:955083-90-6
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Cayman Chemical Company
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Product Name:Myceliothermophin E
CAS:955083-90-6
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Product Name:Myceliothermophin E
CAS:955083-90-6
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| | Myceliothermophin E Basic information |
| Product Name: | Myceliothermophin E | | Synonyms: | Myceliothermophin E;2H-Pyrrol-2-one, 1,5-dihydro-5-(2-methylpropylidene)-3-[[(1S,2R,4aR,6R,8aS)-1,2,4a,5,6,7,8,8a-octahydro-3,4a,6-trimethyl-2-[(1E)-1-methyl-1-propen-1-yl]-1-naphthalenyl]carbonyl]-, (5Z)- | | CAS: | 955083-90-6 | | MF: | C26H37NO2 | | MW: | 395.58 | | EINECS: | | | Product Categories: | | | Mol File: | 955083-90-6.mol |  |
| | Myceliothermophin E Chemical Properties |
| Boiling point | 552.2±50.0 °C(Predicted) | | density | 1.053±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble | | form | A solid | | pka | 11.88±0.40(Predicted) |
| | Myceliothermophin E Usage And Synthesis |
| Definition | ChEBI: Myceliothermophin E is a member of hexahydronaphthalenes and a polyketide. | | Biological Activity | Myceliothermophin E is a polyketide-amino acid hybrid fungal metabolite that has been found in T. thermophilus and has anticancer and antimicrobial activities.1,2 It is cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively).1 Myceliothermophin E is active against methicillin-resistant, but not -sensitive, S. aureus (MICs = 15.8 and >100 μM, respectively).2 | | References | 1.Gao, Y.-L., Zhang, M.-L., Wang, X., et al.Isolation and characterization of a new cytotoxic polyketide-amino acid hybrid from Thermothelomyces thermophilus ATCC 42464Nat. Prod. Res.Epub ahead of print(2019)
2.Wang, X., Zhao, L., Liu, C., et al.New tetramic acids comprising of decalin and pyridones from Chaetomium olivaceum SD-80A with antimicrobial activityFront. Microbiol.102958(2020) |
| | Myceliothermophin E Preparation Products And Raw materials |
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