| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:Aumitin
CAS:946293-78-3
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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| | Aumitin Basic information |
| Product Name: | Aumitin | | Synonyms: | Aumitin;inhibit,Autophagy,Aumitin,Inhibitor;Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]- | | CAS: | 946293-78-3 | | MF: | C24H20ClN5O | | MW: | 429.9 | | EINECS: | | | Product Categories: | | | Mol File: | 946293-78-3.mol |  |
| | Aumitin Chemical Properties |
| density | 1.364±0.06 g/cm3(Predicted) | | pka | 12.36±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | Aumitin Usage And Synthesis |
| Biological Activity | Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1]. | | References | [1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022. |
| | Aumitin Preparation Products And Raw materials |
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