| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:FT895
CAS:2225728-57-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | FT-895) Basic information |
| Product Name: | FT-895) | | Synonyms: | 1H-Isoindole-4-carboxamide, 2,3-dihydro-N-hydroxy-1,1-dimethyl-2-[5-(trifluoromethyl)-2-pyrazinyl]-;FT-895);FT895
(FT 895 | | CAS: | 2225728-57-2 | | MF: | C16H15F3N4O2 | | MW: | 352.31 | | EINECS: | | | Product Categories: | | | Mol File: | 2225728-57-2.mol |  |
| | FT-895) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (354.80 mM; Need ultrasonic) | | form | Solid | | color | White to light yellow |
| | FT-895) Usage And Synthesis |
| Biological Activity | FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1].
FT895 is a highly selective HDAC11 inhibitor showing greater than 1000-fold selectivity against the other 10 members of the HDAC family[1]. | | References | [1]. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147. |
| | FT-895) Preparation Products And Raw materials |
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