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| | dTAG-13 Basic information |
| Product Name: | dTAG-13 | | Synonyms: | dTAG-13;FKBP12 PROTAC DTAG-13;2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-3-(3,4-dimethoxyphenyl)-1-[2-[2-[[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]amino]-2-oxoethoxy]phenyl]propyl ester, (2S)-;(2S)-(1R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)amino)-2-oxoethoxy)phenyl)propyl 1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate, d-TAG-13;(1R)-3-(3,4-dimethoxyphenyl)-1-(2-{[(6-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}hexyl)carbamoyl]methoxy}phenyl)propyl (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate | | CAS: | 2064175-41-1 | | MF: | C57H68N4O15 | | MW: | 1049.17 | | EINECS: | | | Product Categories: | | | Mol File: | 2064175-41-1.mol |  |
| | dTAG-13 Chemical Properties |
| Melting point | 106-111°C | | Boiling point | 1134.0±65.0 °C(Predicted) | | density | 1.260±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMF (Slightly), Methanol (Slightly) | | form | Solid | | pka | 10.70±0.40(Predicted) | | color | White to Off-White |
| | dTAG-13 Usage And Synthesis |
| Uses | dTAG-13 is a degradation tag which was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research. | | storage | Store at -20°C |
| | dTAG-13 Preparation Products And Raw materials |
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