Company Name: |
United States Biological
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Tel: |
1-800-520-3011 |
Email: |
sales@advtechind.com |
Products Intro: |
Product Name:Prothrombin, Bovine
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Company Name: |
Creative Enzymes
|
Tel: |
1-516-855-7709 |
Email: |
info@creative-enzymes.com |
Products Intro: |
Product Name:Human Prothrombin CAS:9001-26-7
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| PROTHROMBIN Basic information |
Product Name: | PROTHROMBIN | Synonyms: | COAGULATION FACTOR II, HUMAN;FACTOR II;HUMAN PROTHROMBIN;PROTHROMBIN;PROTHROMBIN (BOVINE);PROTHROMBIN FROM HUMAN PLASMA;PROTHROMBIN, HUMAN;PROTHROMBIN, HUMAN PLASMA | CAS: | 9001-26-7 | MF: | | MW: | 0 | EINECS: | 232-592-3 | Product Categories: | proteins | Mol File: | Mol File | ![PROTHROMBIN Structure]() |
| PROTHROMBIN Chemical Properties |
storage temp. | −20°C | form | lyophilized powder |
Hazard Codes | B | WGK Germany | 3 | HS Code | 3002120000 |
| PROTHROMBIN Usage And Synthesis |
Definition | The precursor of the enzyme
thrombin, a proteinaceous component of blood
plasma that is converted into thrombin by the blood-
clotting mechanism when activated at the site of an
open wound. | Purification Methods | Prothrombin is purified by two absorptions on a barium citrate adsorbent, followed by decomposition of the adsorbents with a weak carboxylic cation-exchanger (Amberlite IRF-97), isoelectric precipitation (pH 4.7-4.9) and further purification by chromatography on Sephadex G-200 or IRC-50. Finally it is recrystallised from a 1% solution adjusted to pH 6.0-7.0 and partial lyophilisation to ca 1/5 to 1/10th volume and set aside at 2-5o to crystallise. Occasionally seeding is required. [Miller Biochemical Preparations 13 49 1971.] |
| PROTHROMBIN Preparation Products And Raw materials |
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