| Company Name: |
Merck KGaA
|
| Tel: |
(+86) 21 2033 8288 |
| Email: |
sigmaname@qq.com |
| Products Intro: |
Product Name:Prothrombin, Human Plasma
CAS:9001-26-7
|
| Company Name: |
United States Biological
|
| Tel: |
1-800-520-3011 |
| Email: |
sales@advtechind.com |
| Products Intro: |
Product Name:Prothrombin, Bovine
|
|
| | PROTHROMBIN Basic information |
| Product Name: | PROTHROMBIN | | Synonyms: | COAGULATION FACTOR II, HUMAN;FACTOR II;HUMAN PROTHROMBIN;PROTHROMBIN;PROTHROMBIN (BOVINE);PROTHROMBIN FROM HUMAN PLASMA;PROTHROMBIN, HUMAN;PROTHROMBIN, HUMAN PLASMA | | CAS: | 9001-26-7 | | MF: | | | MW: | 0 | | EINECS: | 232-592-3 | | Product Categories: | proteins | | Mol File: | Mol File | ![PROTHROMBIN Structure]() |
| | PROTHROMBIN Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | Water Solubility | water: soluble |
| Hazard Codes | B | | WGK Germany | 3 | | HS Code | 3002120000 |
| | PROTHROMBIN Usage And Synthesis |
| Definition | The precursor of the enzyme
thrombin, a proteinaceous component of blood
plasma that is converted into thrombin by the blood-
clotting mechanism when activated at the site of an
open wound. | | Purification Methods | Prothrombin is purified by two absorptions on a barium citrate adsorbent, followed by decomposition of the adsorbents with a weak carboxylic cation-exchanger (Amberlite IRF-97), isoelectric precipitation (pH 4.7-4.9) and further purification by chromatography on Sephadex G-200 or IRC-50. Finally it is recrystallised from a 1% solution adjusted to pH 6.0-7.0 and partial lyophilisation to ca 1/5 to 1/10th volume and set aside at 2-5o to crystallise. Occasionally seeding is required. [Miller Biochemical Preparations 13 49 1971.] |
| | PROTHROMBIN Preparation Products And Raw materials |
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