| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:YAP-TEAD-IN-1 TFA
CAS:1659305-79-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:YAP-TEAD-IN-1 TFA
CAS:1659305-79-9
Purity:98% Package:5mg;10mg;50mg
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:(S)-4-((S)-1-((S)-1-((S)-2-((3S,6S,9S,12R,18S,21S,24S,27S,30S,35AS)-18-((S)-2-((S)-1-((S)-2-Acetamido-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-(3-chlorophenyl)propanamido)-27-(4-aminobutyl)-9-benzyl-30-butyl-24-(3-guanidinopropyl)-6-(hydroxymethyl)-21-isobutyl-3-methyl-1,4,7,10,19,22,25,28,31-nonaoxodotriacontahydro-1H-pyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclotritriacontine-12-carboxamido)-6-aminohexanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-5-amino-5-oxope
CAS:1659305-79-9
Purity:97% Package:25mg;50mg;100mg Remarks:BD01129922
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| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
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sales@invivochem.cn |
| Products Intro: |
Product Name:YAP-TEAD-IN-1 TFA
CAS:1659305-79-9
Purity:98% HPLC Package:1mg Remarks:V39633
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:YAP-TEAD-IN-1 TFA
CAS:1659305-79-9
Package:10mg/RMB 1650
|
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| | YAP-TEAD-IN-1 TFA Basic information |
| Product Name: | YAP-TEAD-IN-1 TFA | | Synonyms: | YAP-TEAD-IN-1 TFA;YAP-TEAD (Peptide 17).TFA;(S)-4-((S)-1-((S)-1-((S)-2-((3S,6S,9S,12R,18S,21S,24S,27S,30S,35AS)-18-((S)-2-((S)-1-((S)-2-Acetamido-3-methylbutanoyl)pyrrolidine-2-carboxamido)-3-(3-chlorophenyl)propanamido)-27-(4-aminobutyl)-9-benzyl-30-butyl-24-(3-guanidinopropyl)-6-(hydroxymethyl)-21-isobutyl-3-methyl-1,4,7,10,19,22,25,28,31-nonaoxodotriacontahydro-1H-pyrrolo[2,1-p][1,2,5,8,11,14,17,20,23,26,29]dithianonaazacyclotritriacontine-12-carboxamido)-6-aminohexanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)-5-amino-5-oxope | | CAS: | 1659305-79-9 | | MF: | C95H145ClF3N23O23S2 | | MW: | 2133.91 | | EINECS: | | | Product Categories: | | | Mol File: | 1659305-79-9.mol |  |
| | YAP-TEAD-IN-1 TFA Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | YAP-TEAD-IN-1 TFA Usage And Synthesis |
| Biological Activity | YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer polypeptide with higher binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM). | | in vitro | YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the K d < /sub> of His-YAP(1209-426) is determined to be 40 nM. | | target | IC50: 25 nM (YAP-TEAD interaction) |
| | YAP-TEAD-IN-1 TFA Preparation Products And Raw materials |
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