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5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)-

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5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Suppliers list
Company Name: Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.  
Tel: 15990591583
Email:
Products Intro: Product Name:5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)-
CAS:2484741-78-6
Purity:96% HPLC Package:1g;10g;100g
Company Name: Changzhou Bojia Biomedical Technology Co., Ltd.  
Tel: 2122619822
Email: czbjpharma@126.com
Products Intro: CAS:2484741-78-6
Purity:98% Package:10g;100g;500g;1kg;5kg;10kg
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:CBP/p300 ligand 2
CAS:2484741-78-6
Purity:95% Package:5mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:CBP/p300 ligand 2
CAS:2484741-78-6
Package:5mg/RMB 4160
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Basic information
Product Name:5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)-
Synonyms:CBP/p300 ligand 2;5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)-
CAS:2484741-78-6
MF:C27H34F2N8O
MW:524.61
EINECS:
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Mol File:2484741-78-6.mol
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Structure
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Chemical Properties
Boiling point 800.7±65.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
solubility DMSO : 200 mg/mL (381.24 mM; Need ultrasonic)
pka14.19±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Usage And Synthesis
Biological ActivityCBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1]. CBP/p300 ligand 2 (example 229) has no toxicity to LNCaP prostate cancer cells[1].
References[1]. Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. O2020173440A1.
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)- Preparation Products And Raw materials
Tag:5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(4-piperidinyl)-(2484741-78-6) Related Product Information