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L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)

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L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Suppliers list
Company Name: Shenzhen Nexconn Pharmatechs Ltd
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Products Intro: Product Name:Fmoc-Ala-Glu-Asn-Lys-NH2
CAS:220701-06-4
Purity:98% Package:1KG;10KG;50KG
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: CAS:220701-06-4
Purity:99% Package:5KG;1KG
Company Name: Zhejiang Hangyu API Co., Ltd
Tel: +8617531972939
Email: anna@api-made.com
Products Intro: Product Name:Fmoc-Ala-Glu-Asn-Lys-NH2
CAS:220701-06-4
Purity:99% Package:1g;25g;5KG;25KG
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:Fmoc-Ala-Glu-Asn-Lys-NH2
CAS:220701-06-4
Purity:98% Package:$135.9/5mg;$235.9/10mg;Bulk package Remarks:98%
Company Name: Beijing Solarbio Science & Tecnology Co., Ltd.  
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Products Intro: Product Name:Fmoc-AENK-NH2
CAS:220701-06-4
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Basic information
Product Name:L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)
Synonyms:L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI);Fmoc-Ala-Glu-Asn-Lys-NH2;Fmoc-AENK-NH2
CAS:220701-06-4
MF:C33H43N7O9
MW:681.75
EINECS:
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Mol File:220701-06-4.mol
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Structure
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Chemical Properties
Boiling point 1151.3±65.0 °C(Predicted)
density 1.324±0.06 g/cm3(Predicted)
storage temp. -20°C, protect from light, stored under nitrogen
solubility DMSO: 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C)
form Solid
pka4.44±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Usage And Synthesis
Biological ActivityFmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].
References[1]. Zhang Z, et al. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762. Published 2015 Nov 9.
L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI) Preparation Products And Raw materials
Tag:L-Lysinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-α-glutamyl-L-asparaginyl- (9CI)(220701-06-4) Related Product Information
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