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1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-me(261769-44-2)

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名前: TargetMol Chemicals Inc.  
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1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)- 製品概要
化学名:
英語化学名:1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)-
别名:1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)-;BMS-281384;BMS 281384,BMS281384
CAS番号:261769-44-2
分子式:C23H23ClN6O2
分子量:450.92
EINECS:
カテゴリ情報:
Mol File:261769-44-2.mol
1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)-
1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)- 物理性質
融点 209-210.5 °C
沸点 702.9±60.0 °C(Predicted)
比重(密度) 1.34±0.1 g/cm3(Predicted)
貯蔵温度 room temp
溶解性DMSO: 2mg/mL, clear (warmed)
酸解離定数(Pka)11.63±0.46(Predicted)
外見 powder
色white to beige
安全性情報
MSDS Information
1H-Pyrazolo[3,4-b]pyridine-5-carboxamide, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)- Usage And Synthesis
Biochem/physiol ActionsBMS-281384 is a selective and potent phosphodiesterase 5 (PDE 5) inhibitor. BMS-281384 was found to have an IC50 value of 0.8 nM for PDE5 and 47 to 9200-fold selective over other PDEs 1-6.
Tags:261769-44-2