克拉维酸锂
| 中文名称 | 克拉维酸锂 |
|---|---|
| 中文同义词 | 克拉维酸锂;克拉维酸锂;克拉维酸锂;克拉维酸锂 EP标准品;克拉维酸盐锂 |
| 英文名称 | lithium clavulanate |
| 英文同义词 | lithium [2R-(2alpha,3(Z),5alpha)]-3-(2-hydroxyethylidene)-4-oxa-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid lithium salt;(2R,3Z,5β)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid lithium salt;Lithium clavulanoate;purity 96-98%;LithiuM (2R-(2alpha,3(Z),5alpha))-3-(2-hydroxyethylidene)-4-oxa-7-oxo-1-azabicyclo(3.2.0)heptane-2-carboxylate;Lithium (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate;Lithium clavulanate CRS |
| CAS号 | 61177-44-4 |
| 分子式 | C8H10LiNO5 |
| 分子量 | 207.11 |
| EINECS号 | 262-639-3 |
| 相关类别 | |
| Mol文件 | 61177-44-4.mol |
| 结构式 |  |
克拉维酸锂 性质
| 熔点 | >234°C (dec.) |
|---|---|
| 储存条件 | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度 | 加热、超声处理轻微溶于甲醇、轻微溶于水 |
| 形态 | 固体 |
| 颜色 | 浅米色至棕色 |
| 稳定性 | 吸湿性 |
Clavulanate lithium 是一种高效的 β-lactamase 抑制剂，可作为抗生素。
β-lactamase
Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase.
Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L.
Cell Viability Assay
| Cell Line: | L. pneumophila NCTC 1119 |
| Concentration: | 0.25 mg/L, 0.5 mg/L, 1 mg/L |
| Incubation Time: | 0-35 hours |
| Result: | Caused a relatively slow inhibition of growth. |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | HY-A0256B | Clavulanate lithium | 1 mg | 230元 | |
| 2024/08/19 | HY-A0256B | 克拉维酸锂 Clavulanate lithium | 61177-44-4 | 5mg | 500元 |