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Borenpharm Co., Ltd
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027-65563561 |
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Product Name:3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate CAS:59256-52-9 Purity:95% HPLC Package:1g; 5g
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Aikon International Limited
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025-66113011 13155353615 |
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Product Name:2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI) CAS:59256-52-9 Purity:95+% Package:1g;5g;10g
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Shaanxi borno biotechnology co., LTD
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+86-13759708231 |
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Product Name:3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate CAS:59256-52-9 Purity:99% HPLC Package:可分装
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Company Name: |
Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057 |
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service@aiviche.com |
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Product Name:3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate CAS:59256-52-9 Purity:95% Package:1g;1kg
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| 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Basic information |
Product Name: | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate | Synonyms: | 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate;Bispropenoic acid 3,6,9,12-tetraoxatetradecane-1,14-diyl ester;Einecs 261-677-8;2-Propenoic acid, 1,1'-(3,6,9,12-tetraoxatetradecane-1,14-diyl) ester;Bis-acrylate-PEG5;2-Propenoic acid,3,6,9,12-tetraoxatetradecane-1,14-diyl ester (9CI);14-(prop-2-enoyloxy)-3,6,9,12-tetraoxatetradecan-1-yl prop-2-enoate | CAS: | 59256-52-9 | MF: | C16H26O8 | MW: | 346.37 | EINECS: | 2616778 | Product Categories: | | Mol File: | 59256-52-9.mol | ![3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Structure](CAS/GIF/59256-52-9.gif) |
| 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Chemical Properties |
| 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Usage And Synthesis |
Biological Activity | Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| 3,6,9,12-tetraoxatetradecane-1,14-diyl diacrylate Preparation Products And Raw materials |
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