Company Name: |
ShangHai Biochempartner Co.,Ltd
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Tel: |
17754423994 17754423994 |
Email: |
2853530910@QQ.com |
Products Intro: |
Product Name:TP0586532 CAS:2427584-96-9 Purity:98% HPLC LCMS Package:100MG;1G
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Company Name: |
Shanghai Chaolan Chemical Technology Center
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Tel: |
QQ:65489617 15618227136 |
Email: |
info@SuperLan-chem.com |
Products Intro: |
Product Name:TP0586532 CAS:2427584-96-9 Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
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Company Name: |
DC Chemicals
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Tel: |
021-58447131 13564518121 |
Email: |
sales@dcchemicals.com |
Products Intro: |
Product Name:TP0586532 CAS:2427584-96-9 Purity:98% HPLC Package:100mg,250mg,1g
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| TP0586532 Basic information |
Product Name: | TP0586532 | Synonyms: | TP0586532;3-Azabicyclo[3.1.0]hexane-3-butanoic acid, 6-[2-[4-[3-[[2-[(1S)-1-hydroxyethyl]-1H-imidazol-1-yl]methyl]-5-isoxazolyl]phenyl]ethynyl]-, (1α,5α,6-exo,6α)- | CAS: | 2427584-96-9 | MF: | C26H28N4O4 | MW: | 460.53 | EINECS: | | Product Categories: | | Mol File: | 2427584-96-9.mol | ![TP0586532 Structure](CAS/20211123/GIF/2427584-96-9.gif) |
| TP0586532 Chemical Properties |
Boiling point | 712.1±60.0 °C(Predicted) | density | 1.36±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 50 mg/mL (108.57 mM; Need ultrasonic) | form | Solid | pka | 4.44±0.10(Predicted) | color | White to off-white |
| TP0586532 Usage And Synthesis |
Biological Activity | TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1]. | References | [1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964. |
| TP0586532 Preparation Products And Raw materials |
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