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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994 |
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2853530910@QQ.com |
Products Intro: |
Product Name:GRK5-IN-2 CAS:1642839-27-7 Purity:98% HPLC LCMS Package:100MG;1G
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1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- manufacturers
- GRK5-IN-2
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- $46.00 / 5mg
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2024-11-07
- CAS:1642839-27-7
- Min. Order:
- Purity: 99.61%
- Supply Ability: 10g
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| 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- Basic information |
Product Name: | 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- | Synonyms: | 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)-;GRK5-IN-2;metabolic,bicyclic,insulin,kinase,inhibit,Inhibitor,disease,pyridine-based,GRK5 IN 2,GRK-5-IN-2,receptor,GRK5IN2,GRK5;2-(Furan-2-yl)-1-methyl-N-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridin-6-amine | CAS: | 1642839-27-7 | MF: | C20H20N4O4 | MW: | 380.4 | EINECS: | | Product Categories: | | Mol File: | 1642839-27-7.mol | |
| 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- Chemical Properties |
Boiling point | 561.1±60.0 °C(Predicted) | density | 1.32±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 83.33 mg/mL (219.06 mM; Need ultrasonic) | pka | 5.61±0.50(Predicted) | form | Solid | color | Light yellow to brown |
| 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- Usage And Synthesis |
Biological Activity | GRK5-IN-2 (compound 707), a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. GRK5-IN-2 regulates the expression and/or release of insulin and is useful for the metabolic disease research[1]. | References | [1]. Axel Ullrich (Prof. Dr.), et al. Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators. EP2818472A1. |
| 1H-Imidazo[4,5-c]pyridin-6-amine, 2-(2-furanyl)-1-methyl-N-(3,4,5-trimethoxyphenyl)- Preparation Products And Raw materials |
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