E-7820

E-7820 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:E7820
CAS:289483-69-8
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:E7820
CAS:289483-69-8
Purity:99.11% Package:1mg;30USD|5mg;63USD|10mg;80USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:E-7820
CAS:289483-69-8
Purity:0.99summer Package:5KG;1KG Remarks:Summer 618
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:E7820
CAS:289483-69-8
Purity:98% Package:5mg Remarks:V3568
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:E7820;ER68203-00
CAS:289483-69-8
Package:1 mL * 10mM (in DMSO);10 mg;2 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

E-7820 manufacturers

  • E7820
  • E7820 pictures
  • $30.00 / 1mg
  • 2024-11-17
  • CAS:289483-69-8
  • Min. Order:
  • Purity: 99.11%
  • Supply Ability: 10g
E-7820 Basic information
Product Name:E-7820
Synonyms:E-7820;ER 68203-00;3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide;N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide;E 7820; E-7820;CS-2701;ER68203-00;E7820;E-7820;E 7820;289483-69-8;Benzenesulfonamide, 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)-
CAS:289483-69-8
MF:C17H12N4O2S
MW:336.37
EINECS:
Product Categories:
Mol File:289483-69-8.mol
E-7820 Structure
E-7820 Chemical Properties
Boiling point 626.2±65.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:67.0(Max Conc. mg/mL);199.19(Max Conc. mM)
form A crystalline solid
pka8.17±0.30(Predicted)
color Light yellow to light brown
Safety Information
MSDS Information
E-7820 Usage And Synthesis
DescriptionE7820 is a sulfonamide derivative and an angiogenesis inhibitor that inhibits bFGF- and VEGF-stimulated human umbilical vein endothelial cell (HUVEC) proliferation (IC50s = 0.1 and 0.081 μg/ml, respectively). It inhibits bFGF- and VEGF-stimulated tube formation of HUVECs in a concentration-dependent manner (IC50s = 0.2 and 0.24 μg/ml, respectively). E7820 selectively decreases the surface expression and mRNA levels of integrin α2 over CD31 and VE-cadherin in HUVECs. In vivo, E7820 (200 and 400 mg/kg) reduces tumor growth and inhibits angiogenesis in a WiDr colorectal cancer mouse xenograft model. It also reduces tumor weight in a panel of seven human colon, breast, pancreas, and kidney cancer mouse xenograft models, completely inhibits tumor growth in KP-1 pancreatic and LoVo colon cancer mouse xenograft models, and inhibits tumor growth in KP-1 and COLO 320DM mouse orthotopic transplantation models.
storageStore at -20°C
E-7820 Preparation Products And Raw materials
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