| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:MRT-14
CAS:1263131-83-4
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 15221909166 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide
CAS:1263131-83-4
Purity:98% Package:10mg;25mg;50mg;100mg Remarks:BD01517139
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:MRT-14;Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14
CAS:1263131-83-4
Purity:98.55% Package:10 mg;100 mg;200 mg;25 mg;5 mg;50 mg
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| Company Name: |
RD International Technology Co., Limited
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| Tel: |
18024082417 |
| Email: |
market@ubiochem.com |
| Products Intro: |
Product Name:MRT-14
CAS:1263131-83-4
Purity:5mg;10mg;50mg;100mg;250mg;500mg;1g Package:5mg;10mg;50mg;100mg;250mg;500mg;1g
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| | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Basic information |
| Product Name: | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- | | Synonyms: | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy-;MRT-14;Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14;N-(N-(3-Benzamidophenyl)carbamimidoyl)-3,4,5-trimethoxybenzamide | | CAS: | 1263131-83-4 | | MF: | C24H24N4O5 | | MW: | 448.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1263131-83-4.mol | ![Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Structure](CAS/20210305/GIF/1263131-83-4.gif) |
| | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Chemical Properties |
| density | 1.26±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 100 mg/mL (222.98 mM; Need ultrasonic) | | pka | 10.28±0.46(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Usage And Synthesis |
| Biological Activity | MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling[1]. | | References | [1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665. |
| | Benzamide, N-[[[3-(benzoylamino)phenyl]amino]iminomethyl]-3,4,5-trimethoxy- Preparation Products And Raw materials |
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