Company Name: |
Reer Technology (Shanghai) Co., LTD
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Tel: |
021-64400900 15800436310 |
Email: |
bessey@reertech.com |
Products Intro: |
Product Name:L-CARNITINE:HCL(TRIMETHYL-D9, 98%) CAS:2687961-04-0 Purity:98% Package:5 MG Remarks:DLM-10962-5
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Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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Tel: |
021-65675885 18964387627 |
Email: |
customer_service@efebio.com |
Products Intro: |
Product Name:L-Carnitine-d9 (chloride) CAS:2687961-04-0 Purity:95% Package:1mg;5mg;10mg
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Company Name: |
Cayman Chemical Company
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Tel: |
(800) 364-9897 |
Email: |
cayman@caymanchem.com |
Products Intro: |
Product Name:L-Carnitine-d9 (chloride) CAS:2687961-04-0
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| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-, chloride (1:1), (2R)- Basic information |
| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-, chloride (1:1), (2R)- Chemical Properties |
storage temp. | -20°C | solubility | DMF: 15 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml | form | A crystalline solid |
| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-, chloride (1:1), (2R)- Usage And Synthesis |
Biological Activity | L-Carnitine-d9 is intended for use as an internal standard for the quantification of L-carnitine by GC- or LC-MS. L-Carnitine is a conditionally essential nutrient.1 It is obtained from dietary sources or through the metabolism of lysine and methionine.2,3 L-Carnitine facilitates the transport of long-chain fatty acids into the mitochondrial matrix for β-oxidation, has other diverse roles on metabolism, and is involved in the maintenance of coenzyme A stores. Plasma and/or tissue levels of L-carnitine are decreased in primary L-carnitine deficiency, a disorder characterized by impaired fatty acid oxidation, with symptoms varying depending on whether it is systemic or muscle-specific.1 Serum and tissue levels of L-carnitine are also reduced in secondary L-carnitine deficiencies caused by a variety of hereditary defects or acquired disorders. | References | 1.Seim, H., Eichler, K., and Kleber, H.-P.L(-)-Carnitine and its precursor, γ-butyrobetaineNutraceuticals in Health and Disease Prevention217-256(2001)
2.Vaz, F.M., and Wanders, R.J.A.Carnitine biosynthesis in mammalsBiochem. J.361(Pt 3)417-429(2002)
3.Fu, L., Huang, M., and Chen, S.Primary carnitine deficiency and cardiomyopathyKorean. Circ. J.43(12)785-792(2013) |
| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-tri(methyl-d3)-, chloride (1:1), (2R)- Preparation Products And Raw materials |
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