| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:RUVBL1/2 ATPase-IN-1
CAS:423128-55-6
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:RUVBL1/2 ATPase-IN-1
CAS:423128-55-6
Purity:98% HPLC Package:100mg，250mg，1g
|
| Company Name: |
Jingmo (Xiamen) Biotechnology Co., Ltd
|
| Tel: |
13621943973 |
| Email: |
sales@jamxmpharmatech.com |
| Products Intro: |
Product Name:RUVBL1/2 ATPase-IN-1
CAS:423128-55-6
Purity:98% Package:1g;5g;10g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:RUVBL1/2 ATPase-IN-1;RUVBL1/2 ATPaseIN1,inhibit,Inhibitor,selective,RUVBL1/2 ATPase IN 1,cancer,RUVBL1,AAA ATPases,RUVBL2
CAS:423128-55-6
Purity:99.21% Package:1 mg;10 mg;100 mg;2 mg;5 mg
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| | RUVBL1/2 ATPase-IN-1 Basic information |
| Product Name: | RUVBL1/2 ATPase-IN-1 | | Synonyms: | RUVBL1/2 ATPase-IN-1;RUVBL1/2 ATPaseIN1,inhibit,Inhibitor,selective,RUVBL1/2 ATPase IN 1,cancer,RUVBL1,AAA ATPases,RUVBL2;Methanone, [5,7-dimethyl-6-[(4-methylphenyl)methyl]pyrazolo[1,5-a]pyrimidin-3-yl][4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]- | | CAS: | 423128-55-6 | | MF: | C28H28F3N5O | | MW: | 507.55 | | EINECS: | | | Product Categories: | | | Mol File: | 423128-55-6.mol |  |
| | RUVBL1/2 ATPase-IN-1 Chemical Properties |
| density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 10 mg/mL (19.70 mM; ultrasonic and warming and heat to 60°C) | | pka | 1.33±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | RUVBL1/2 ATPase-IN-1 Usage And Synthesis |
| Biological Activity | RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1]. | | References | [1]. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726. |
| | RUVBL1/2 ATPase-IN-1 Preparation Products And Raw materials |
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