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2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)-

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2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MPT0B390
CAS:1817802-18-8
Purity:98.23% Package:1mg;58USD|5mg;148USD|10mg;223USD
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:MPT0B390
CAS:1817802-18-8
Purity:98% HPLC Package:10mg，500mg，1g，5g，10g
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:MPT0B390
CAS:1817802-18-8
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shanghai Guangyang Jiali Biotechnology Co., Ltd
Tel: 13407521611
Email: 46993711@qq.com
Products Intro: CAS:1817802-18-8
Package:2
Company Name: Shanghai Changyu Medical Technology Co. Ltd.  
Tel: +86-13301875428
Email: sales@changyuhe.com
Products Intro: CAS:1817802-18-8
Purity:98% Package:1g;10g

2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- manufacturers

  • MPT0B390
  • MPT0B390 pictures
  • $58.00 / 1mg
  • 2024-11-19
  • CAS:1817802-18-8
  • Min. Order:
  • Purity: 98.23%
  • Supply Ability: 10g
2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Basic information
Product Name:2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)-
Synonyms:2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)-;MPT0B390;colorectal cancer,HDAC,Inhibitor,inhibit,HDAC inhibitory ability,MPT0B390,colon cancer,Histone deacetylases,HCT116,metastasis,TIMP3,angiogenesis;MPT0B390, 10 mM in DMSO
CAS:1817802-18-8
MF:C17H17N3O5S
MW:375.4
EINECS:
Product Categories:
Mol File:1817802-18-8.mol
2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Structure
2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Chemical Properties
density 1.452±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (665.96 mM; Need ultrasonic)
pka8.49±0.23(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Usage And Synthesis
Biological ActivityMPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM[1].
References[1]. Han-Li Huang, et al. TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis. Theranostics. 2019 Sep 18;9(22):6676-6689.
2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)- Preparation Products And Raw materials
Tag:2-Propenamide, 3-[2,3-dihydro-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-hydroxy-, (2E)-(1817802-18-8) Related Product Information