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4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]-

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4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Suppliers list
Company Name: Increland Biotechnology Co.,Ltd  
Tel: 086-18428181580 18428181580
Email: chenxing@cyclobiotech.com
Products Intro: Product Name:Vemtoberant
CAS:2169905-68-2
Purity:98% HPLC Package:0.5g, 5g
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:Vemtoberant
CAS:2169905-68-2
Purity:0 Package:50mg/RMB 19800;100mg/RMB 25500;25mg/RMB 15000
4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Basic information
Product Name:4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]-
Synonyms:4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]-;Vemtoberant
CAS:2169905-68-2
MF:C29H37N3O8S2
MW:619.75
EINECS:
Product Categories:
Mol File:2169905-68-2.mol
4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Structure
4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Chemical Properties
Boiling point 851.6±75.0 °C(Predicted)
density 1.44±0.1 g/cm3(Predicted)
form Solid
pka13.70±0.20(Predicted)
color Off-white to light yellow
Safety Information
MSDS Information
4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Usage And Synthesis
DescriptionVemtoberant, also known as APD418, is a β3-adrenergic receptor (AdrR) antagonist for treatment of decompensated heart failure. Unlike current inotrope therapie , Vemtoberant improves cardiac contractility with minimal negative impact on heart rate, blood pressure, and myocardial oxygen consumption. Vemtoberant has undergone Phase 2 trials for those in heart failure with reduced ejection fraction.
4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]- Preparation Products And Raw materials
Tag:4(1H)-Quinolinone, 1-ethyl-3-[[(3R)-3-[[(2S)-2-hydroxy-3-[3-(methylsulfonyl)phenoxy]propyl]amino]-1-oxa-8-azaspiro[4.5]dec-8-yl]sulfonyl]-(2169905-68-2) Related Product Information