| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:YM-430;YM 430
CAS:153192-22-4
Purity:98% Package:5 mg
|
| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
|
| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:153192-22-4
CAS:153192-22-4
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
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| Company Name: |
CHEMICAL LAND21
|
| Tel: |
82- 2 -783 - 8063 |
| Email: |
sales21@chemicalland21.com |
| Products Intro: |
|
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| | YM 15430-1 Basic information |
| Product Name: | YM 15430-1 | | Synonyms: | YM 15430-1;YM-15430;YM-15430-2;YM-15430-3;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[4-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]butyl] 5-methyl ester, (4S)- | | CAS: | 153192-22-4 | | MF: | C29H35N3O8 | | MW: | 553.6 | | EINECS: | | | Product Categories: | | | Mol File: | 153192-22-4.mol |  |
| | YM 15430-1 Chemical Properties |
| Boiling point | 729.3±60.0 °C(Predicted) | | density | 1.240±0.06 g/cm3(Predicted) | | pka | 13.98±0.20(Predicted) |
| | YM 15430-1 Usage And Synthesis |
| Description | YM-430, also known as YM-15430; YM-154301; is a dual of β1 adrenergic receptor antagonist and calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent, because of its dual activities. YM430 (10(-8)-10(-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 nM. In anesthetized rats, YM430 (10-100 mg/kg PO) inhibited arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg PO. YM430 may be of value in the treatment of various types of angina pectoris such as variant and stable angina. |
| | YM 15430-1 Preparation Products And Raw materials |
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