| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:SKF89976A HCl
CAS:85375-85-5
Purity:详情请点击官网 Package:1 mg
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| | SK&F 89976-A Basic information |
| Product Name: | SK&F 89976-A | | Synonyms: | 1-(4,4-Diphenyl-3-butenyl)-3-piperidinecarboxylic acid;SKF-89976;3-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-buten-1-yl)- | | CAS: | 85375-85-5 | | MF: | C22H25NO2 | | MW: | 335.44 | | EINECS: | | | Product Categories: | | | Mol File: | 85375-85-5.mol |  |
| | SK&F 89976-A Chemical Properties |
| Boiling point | 531.4±50.0 °C(Predicted) | | density | 1.121±0.06 g/cm3(Predicted) | | pka | 3.87±0.20(Predicted) |
| | SK&F 89976-A Usage And Synthesis |
| Description | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. | | Definition | ChEBI: 1-(4,4-diphenylbut-3-enyl)-3-piperidinecarboxylic acid is a diarylmethane. |
| | SK&F 89976-A Preparation Products And Raw materials |
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