| Company Name: |
Puripharm Co., Ltd.
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| Tel: |
0572-2745768-1 13167223168 |
| Email: |
sales@puripharm.com |
| Products Intro: |
Product Name:PHYTOSTEROLS
CAS:949109-75-5
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| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
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| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:Phytosterols
CAS:949109-75-5
Purity:98%+ HPLC Package:10mg，500mg，1g，2g，5g，10mg，more
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| | PLANTSTEROLS Basic information |
| Product Name: | PLANTSTEROLS | | Synonyms: | PLANTSTEROLS;Cardioaid m;Sterols, phytosterols;Pygeum Bark Extract | | CAS: | 949109-75-5 | | MF: | | | MW: | 0 | | EINECS: | 619-079-3 | | Product Categories: | | | Mol File: | Mol File | ![PLANTSTEROLS Structure]() |
| | PLANTSTEROLS Chemical Properties |
| density | 1.05 at 23℃ | | vapor pressure | 0-0Pa at 25℃ | | form | Powder | | LogP | 9.4 at 40℃ |
| | PLANTSTEROLS Usage And Synthesis |
| Anticancer Research | Plant sterols (PS)/carbon steroid alcohols (Otaegui-Arrazola et al. 2010) are vital components of plant cell membranes and are key components of plant plasma membrane microdomains. Campesterol, stigmasterol, and β-sitosterol are most abundant PS in human diet (Roche et al. 2008). Biochemical and molecular effects of PS make them strong candidates for breast cancer therapy; there are compelling evidences for the same (Grattan Jr 2013). Estrogen is a well-recognized mediator of breast cells growth, and it also plays key role in etiology of breast cancer (Begg et al. 1987; Jordan 2000; Finlay-Schultz and Sartorius 2015). Increased amounts of estrogen are a potential risk factor for breast cancer (Gutendorf and Westendorf 2001; Rossouw et al. 2002; Hankinson et al. 2004; Touillaud et al. 2005). Touillaud et al. (2005) also stated that intake of β-sitosterol relates to greater occurrence of estrogen receptor-positive (ER+) than estrogen negative (ER-) breast cancer (OR 0.49; 95% CI 0.18–0.98). β-Sitosterol binds competitively to both α and β forms of ER. While, plant stanols and stanol esters failed to stimulate estrogen-responsive growth in MCF-7 lines (Baker et al. 1999). However, an evidence from reporter gene array studies in human breast cancer lines conforms PS as a weak selective estrogen receptor modulators (Gutendorf and Westendorf 2001). |
| | PLANTSTEROLS Preparation Products And Raw materials |
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