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| | ETHANOL,2-[2-(2-PHENOXYETHOXY Basic information |
| Product Name: | ETHANOL,2-[2-(2-PHENOXYETHOXY | | Synonyms: | ETHANOL,2-[2-(2-PHENOXYETHOXY;2-[2-(2-Phenoxyethoxy)ethoxy]ethanol;Triethylene glycol monophenyl ether;Ethanol, 2-[2-(2-phenoxyethoxy)ethoxy]-;Ph-PEG3;2-(2-(2-Phenoxyethoxy)ethoxy)ethan-1-ol | | CAS: | 7204-16-2 | | MF: | C12H18O4 | | MW: | 226.27 | | EINECS: | | | Product Categories: | | | Mol File: | 7204-16-2.mol |  |
| | ETHANOL,2-[2-(2-PHENOXYETHOXY Chemical Properties |
| Boiling point | 74-77 °C(Press: 0.05 Torr) | | density | 1.097±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | ETHANOL,2-[2-(2-PHENOXYETHOXY Usage And Synthesis |
| Biological Activity | Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | ETHANOL,2-[2-(2-PHENOXYETHOXY Preparation Products And Raw materials |
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