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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

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3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Suppliers list
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008657128800458; +8615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide (Fandachem)
CAS:199666-03-0
Purity:As coa Package:As request Remarks:199666-03-0
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:Ro 61-8048
CAS:199666-03-0
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: sales@coreychem.com
Products Intro: Product Name:3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
CAS:199666-03-0
Purity:98% Package:1ASSAYS;1USD
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Ro 61-8048
CAS:199666-03-0
Purity:>98% Package:50mg Remarks:BOC Sciences also provides custom synthesis services for Ro 61-8048.
Company Name: Chengdu Feibo Pharm Technology Co., Ltd
Tel: 15982321820
Email: abby@arkpharm.com
Products Intro: Product Name:3,4-DIMETHOXY-N-(4-(3-NITROPHENYL)THIAZOL-2-YL)BENZENESULFONAMIDE
CAS:199666-03-0
Purity:97% Package:5g;10g;25g

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide manufacturers
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Basic information
Product Name:3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
Synonyms:Ro 61-8048, >=98%;RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048;RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;KMO Inhibitor I, Ro 61-8048;3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide
CAS:199666-03-0
MF:C17H15N3O6S2
MW:421.45
EINECS:
Product Categories:Inhibitors
Mol File:199666-03-0.mol
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Structure
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Chemical Properties
Melting point 185℃
Boiling point 627.4±65.0 °C(Predicted)
density 1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
solubility DMSO: ≥15mg/mL
form Yellow solid
pka6.29±0.10(Predicted)
color faint yellow to yellow
Safety Information
Hazard Codes T
Risk Statements 25-36
Safety Statements 26-45
WGK Germany 3
MSDS Information
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Usage And Synthesis
UsesRo 61-8048 is a potent and competitive kynurenine 3-monooxygenase (KMO) inhibitor.
DefinitionChEBI: Ro 61-8048 is a C-nitro compound.
Biological ActivityPotent and competitive kynurenine 3-hydroxylase inhibitor (K i = 4.8 nM, IC 50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.
Biochem/physiol ActionsRo 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.
storage+4°C
3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide Preparation Products And Raw materials
Tag:3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide(199666-03-0) Related Product Information
(S)-2-(4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(1-((S)-2,3-dihydroxypropyl)-1H-pyrazol-3-yl)-4-methylpentanamide AZD6738 SGC707 MS023 2-(2-Chlorophenyl)-4-(3-(diMethylaMino)phenyl)-5-Methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione Enasidenib Epacadostat (INCB024360) indoleaMine-2,3-dioxygenase inhibitor INCB024360 LLY-507 4-BroMo-N-(4-broMophenyl)-3-[[(phenylMethyl)aMino]sulfonyl]benzaMide DBeQ Ro 3306 Bisindoylmaleimide X RO495 3,4-difluoro-2-(2-fluoro-4-iodophenylaMino)-N-(2-hydroxyethoxy)-5-((3-oxoMorpholino)Methyl)benzaMide ROC-325 RO2959 Hydrochloride