| Company Name: |
Shanghai alkynechem Co., Ltd.
|
| Tel: |
086-021-15821262312 15821262312 |
| Email: |
info@alkynechem.com |
| Products Intro: |
Product Name:1-Bromohept-2-yne
CAS:18495-26-6
Purity:97% Package:1kg
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| Company Name: |
U-Chemo Scientific(Shanghai) Co.,Ltd
|
| Tel: |
021-58380326 13585932672 |
| Email: |
3251669772@qq.com |
| Products Intro: |
Product Name:1-bromohept-2-yne
CAS:18495-26-6
Purity:95%/97% Package:100G/1KG/10KG/100KG Remarks:PI051
|
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| | 1-bromohept-2-yne Basic information |
| | 1-bromohept-2-yne Chemical Properties |
| Boiling point | 178.72°C (estimate) | | density | 1.4129 (rough estimate) | | refractive index | 1.4878 |
| | 1-bromohept-2-yne Usage And Synthesis |
| Uses | 2-Heptynyl Bromide is an intermediate in the synthesis of 2-(2-Heptynylthio)phenol Acetate (H288500), which is an O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1. |
| | 1-bromohept-2-yne Preparation Products And Raw materials |
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