| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:(R)-(+)-SKF-38393 hydrochloride
CAS:81702-42-3
Purity:>=98% (HPLC), solid Package:100MG Remarks:S101-100MG
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:(R)-(+)-SKF-38393Hydrochloride
CAS:81702-42-3
Purity:NULL Package:10mg;5mg;100mg;5mg Remarks:NULL
|
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| | (R)-(+)-SKF-38393 hydrochloride Basic information |
| | (R)-(+)-SKF-38393 hydrochloride Chemical Properties |
| Melting point | 244-246 °C | | solubility | 0.1 M HCl: soluble1.2mg/mL | | form | solid | | color | off-white to light tan | | optical activity | [α]22/D +16.1°, c = 1.2 in methanol(lit.) |
| | (R)-(+)-SKF-38393 hydrochloride Usage And Synthesis |
| Uses | (R)-(+)-SKF-38393 Hydrochloride is the active enantiomer of (±)-SKF-38393, a D1 dopamine receptor agonist. | | Uses | (R)-(+)-SKF-38393 hydrochloride has been used as a D1 dopamine receptor agonist to study its effect on the sleep-wake pattern of macaques rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). | | Biochem/physiol Actions | (R)-(+)-SKF-38393 hydrochloride is a D1 dopamine receptor agonist and an active enantiomer of (±)-SKF-38393. It enhances pertussis toxin-insensitive and protein kinase A-mediated glutamate release in the hippocampal neurons. SKF-38393, a?benzazepine derivative, exhibits anorectic effects. |
| | (R)-(+)-SKF-38393 hydrochloride Preparation Products And Raw materials |
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