Company Name: |
LETOPHARM LIMITED
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Tel: |
+86-21-5821 5861 |
Email: |
sales@letopharm.com |
Products Intro: |
Product Name:CAY10626 CAS:1202884-94-3
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Company Name: |
BOC Sciences
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Tel: |
16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:CAY10626 CAS:1202884-94-3 Purity:98% Package:1G;10G;100G Remarks:Phosphatidylinositol 3-kinases (PI3K) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, whic
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Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Tel: |
18818260767 |
Email: |
sales@chemegen.com |
Products Intro: |
Product Name:CAY10626 CAS:1202884-94-3 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| PI3K inhibitor Basic information |
Product Name: | PI3K inhibitor | Synonyms: | PI3K inhibitor;Antitumor Drug;CAY10626;BenzaMide, N-[2-(diMethylaMino)ethyl]-N-Methyl-4-[[[[4-[4-(4-Morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyriMidin-2-yl]phenyl]aMino]carbonyl]aMino]-;N-[2-(dimethylamino)ethyl]-N-methyl-4-[({4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}carbamoyl)amino]benzamide;PI3K-IN-22 | CAS: | 1202884-94-3 | MF: | C31H35F3N8O3 | MW: | 624.66 | EINECS: | | Product Categories: | | Mol File: | 1202884-94-3.mol | |
| PI3K inhibitor Chemical Properties |
density | 1.35±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml | form | A crystalline solid | pka | 13.74±0.70(Predicted) |
| PI3K inhibitor Usage And Synthesis |
Description | The PI3Kinases are important downstream effectors of KRAS signaling. In preclinical studies, buparlisib (BKM120), a PI3K inhibitor, when combined with MEK
inhibitor (PD1056309) led to significant synergistic activity in KRAS mutant
NSCLC cell lines. | Definition | ChEBI: CAY10626 is a member of ureas. |
| PI3K inhibitor Preparation Products And Raw materials |
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