Company Name: |
Ralington Pharma
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Tel: |
+91-7948911722 +91-9687771722 |
Email: |
info@ralingtonpharma.com |
Products Intro: |
Product Name:Tigecycline monohydrochloride CAS:197654-04-9 Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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Company Name: |
SPIRO PHARMA
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Tel: |
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Email: |
eric_feng1954@126.com |
Products Intro: |
Product Name:Tigecycline (hydrochloride) CAS:197654-04-9 Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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Tel: |
010-60605840 18892239720 |
Email: |
psaitong@jm-bio.com |
Products Intro: |
Product Name:Tigecycline hydrochloride CAS:197654-04-9 Purity:98% Package:10mg;50mg
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| Tigecycline Hydrochloride Basic information |
| Tigecycline Hydrochloride Chemical Properties |
storage temp. | Store at -20°C | solubility | Soluble in DMSO | form | Powder |
| Tigecycline Hydrochloride Usage And Synthesis |
Biological Activity | Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline against E. coli (strain MG1655) is approximately 125 ng/mL. The MIC50 and MIC90 for Acinetobacter baumannii (A. baumannii) were 1 and 2 mg/L, respectively. | in vitro | Tigecycline (0.63-30 μM, preincubated for 4 days, treated for 72 h) inhibits AML2 cells and HL-60 cells with IC 50 s of 4.72±0.54 and 3.06±0.85 μM (freshly prepared). | in vivo | Tigecycline (50 mg/kg; intraperitoneal injection; twice a day; for 11 days) reduces tumor volume and weight in NOD/SCID mice. | target | Mean MIC: 125 ng/mL ( E. coli ) MIC50: 1 mg/mL ( A. baumannii ) MIC90: 2 mg/mL ( A. baumannii ) |
| Tigecycline Hydrochloride Preparation Products And Raw materials |
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