Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Anti-CD69 Purity:Prestige Antibodies P Remarks:HPA050525
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| ANTI-HUMAN CD69 Basic information |
Product Name: | ANTI-HUMAN CD69 | Synonyms: | ANTI-HUMAN AIM;ANTI-HUMAN ACTIVATED INDUCER MOLECULE;ANTI-AIM (HUMAN);ANTI-CD69;ANTI-CD69 (HUMAN);ANTI-CD69, HUMAN (MOUSE);ANTI-CD69 MOUSE MAB;ANTI-HUMAN CD69 | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| ANTI-HUMAN CD69 Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
Hazard Codes | Xn | Risk Statements | 22 |
| ANTI-HUMAN CD69 Usage And Synthesis |
Uses | The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. | General Description | Cluster of differentiation 69 (CD69) is a type II integral membrane protein, encoded by the gene mapped to human chromosome 12p13.31. CD69 is a member of the C-type lectin family of surface receptors. The encoded protein is expressed in all bone marrow-derived cells, with the exception of erythrocytes. | Biochem/physiol Actions | Cluster of differentiation 69 (CD69) exerts a pro-inflammatory effect by activating leukocytes. In humans, CD69 negatively regulates immune reactivity. Knockout/deficiency of the gene increases the risk of susceptibility to autoimmune and chronic inflammatory diseases. The encoded protein might act as a prognostic marker for bendamustine response in chronic lymphocytic leukemia (CLL) patients. CD69 facilitates natural killer (NK) cell function. In addition, it also helps in activation and differentiation of a wide variety of hematopoietic cells. |
| ANTI-HUMAN CD69 Preparation Products And Raw materials |
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