| Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:trans-Ned-19
CAS:1354235-96-3
Package:50Mg,5Mg
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| | trans-Ned 19 Basic information |
| Product Name: | trans-Ned 19 | | Synonyms: | trans-Ned 19;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-;transNed 19,trans Ned 19 | | CAS: | 1354235-96-3 | | MF: | C30H31FN4O3 | | MW: | 514.59 | | EINECS: | | | Product Categories: | Aromatics, Heterocycles, Indole Derivatives, Inhibitors, Fluorescent Labels & Indicators, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics;Fluorescent Labels & Indicators;Heterocycles;Indole Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 1354235-96-3.mol |  |
| | trans-Ned 19 Chemical Properties |
| Melting point | 168-173°C | | Boiling point | 715.1±60.0 °C(Predicted) | | density | 1.316±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Methanol | | form | Solid | | pka | 2.17±0.40(Predicted) | | color | Yellow |
| | trans-Ned 19 Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. | | Definition | ChEBI: Trans-Ned 19 is a member of the class of beta-carbolines that is 2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid in which one of the methylene protons at position 1 has been replaced by a 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl group. It has a role as a nicotinic acid adenine dinucleotide phosphate receptor antagonist. It is a member of beta-carbolines, an alpha-amino acid, a monomethoxybenzene, a member of monofluorobenzenes and a N-arylpiperazine. | | storage | Store at -20°C |
| | trans-Ned 19 Preparation Products And Raw materials |
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