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Shanghai Hongye Biotechnology Co. Ltd
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Product Name:17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
CAS:195503-20-9
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
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0571-85361029 |
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synstar518@163.com |
| Products Intro: |
Product Name:17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
CAS:195503-20-9
Purity:0.98 Package:100mg、500mg、1g、5g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
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Product Name:17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive
CAS:195503-20-9
Purity:98% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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15002134094 |
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Product Name:17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
CAS:195503-20-9
Purity:0 Package:1mg
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| Company Name: |
Cayman Chemical Company
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(800) 364-9897 |
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cayman@caymanchem.com |
| Products Intro: |
Product Name:17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
CAS:195503-20-9
Package:>=98% Remarks:10010111
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| | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Basic information |
| Product Name: | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | | Synonyms: | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive;SPNWWFJGYHYDNY-HCAGXNQISA-N;17-trifluoromethylphenyl trinor Prostaglandin F2.alpha. methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester;17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Exclusive;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, methyl ester, (5Z)- | | CAS: | 195503-20-9 | | MF: | C25H33F3O5 | | MW: | 470.52 | | EINECS: | | | Product Categories: | | | Mol File: | 195503-20-9.mol |  |
| | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Chemical Properties |
| Boiling point | 556.7±50.0 °C(Predicted) | | density | 1.246±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): .15 mg/ml | | pka | 14.25±0.20(Predicted) |
| | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Usage And Synthesis |
| Description | Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.1,2,3 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. | | References | 1. Samuelsson, B., Goldyne, M., Granstr?m, E., et al. Prostaglandins and thromboxanes Annu. Rev. Biochem. 47,997-1029(1978).
2. Speroff, L., and Ramwell, P.W. Prostaglandins in reproductive physiology Am. J. Obstet. Gynecol. 107(7),1111-1130(1970).
3. Crankshaw, D.J., and Gaspar, V. Pharmacological characterization in vitro of prostanoid receptors in the myometrium of nonpregnant ewes J. Reprod. Fertil. 103(1),55-61(1995). |
| | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Preparation Products And Raw materials |
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