| Company Name: |
ShangHai Biochempartner Co.,Ltd
|
| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:Cl-Amidine
CAS:913723-61-2
Purity:98% HPLC LCMS Package:100mg;1g
|
| Company Name: |
Shanghai Biopharmaleader Co., Ltd.
|
| Tel: |
+86 18721201413 |
| Email: |
sales@biopharmaleader.com |
| Products Intro: |
Product Name:Cl-Amidine
CAS:913723-61-2
Purity:98%HPLC Package:10g,100g
|
|
| | Cl-Amidine Basic information |
| Product Name: | Cl-Amidine | | Synonyms: | Cl-Amidine;N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamideN-;N-[(1S)-1-(Aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]benzamide;N-alpha-Benzoyl-N5-(2-chloro-1-iminoethyl)-1-ornithine amide;Benzamide, N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-;Cl amidine,Clamidine;N-BCl-I-OA cpd;(S)-N-(1-Amino-5-(2-chloroacetimidamido)-1-oxopentan-2-yl)benzamide | | CAS: | 913723-61-2 | | MF: | C14H19ClN4O2 | | MW: | 310.78 | | EINECS: | | | Product Categories: | | | Mol File: | 913723-61-2.mol |  |
| | Cl-Amidine Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | Cl-Amidine Usage And Synthesis |
| Definition | ChEBI: Cl-Amidine is a member of benzenes. | | Biological Activity | Cl-amidine is an orally active PAD inhibitor with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3 and PAD4, respectively.It induces apoptosis in cancer cells. And Cl-Amidine blocks histone 3 citrullination and neutrophil extracellular trap formation and improves survival in mice with sepsis. | | target | IC50: 0.8 μM (PAD1), 5.9 μM (PAD4), 6.2 μM (PAD3). |
| | Cl-Amidine Preparation Products And Raw materials |
|