Log in | Join Free | china | japan | germany

2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-

Request For Quotation
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:ADX88178
CAS:1235318-89-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Shandong chuangyingchemical Co., Ltd.
Tel: 18853181302
Email: sale@chuangyingchem.com
Products Intro: Product Name:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
CAS:1235318-89-4
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
CAS:1235318-89-4
Purity:Min98%HPLC/LC Package:1KG;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:ADX88178
CAS:1235318-89-4
Package:1 mg；10 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054
Email: trendseenbio@gmail.com
Products Intro: Product Name:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
CAS:1235318-89-4
Purity:99% Package:1kg；25kg
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Basic information
Product Name:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
Synonyms:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-;5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine;4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-2-Pyrimidinamine;ADX88178;ADX-88178;5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine;ADX88178, >98%;ADX-88178;ADX 88178;ADX88178
CAS:1235318-89-4
MF:C12H12N6S
MW:272.33
EINECS:
Product Categories:
Mol File:1235318-89-4.mol
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Structure
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Chemical Properties
storage temp. Store at -20°C
solubility DMSO:16.67(Max Conc. mg/mL);61.21(Max Conc. mM)
form Solid
color White to off-white
Safety Information
MSDS Information
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Usage And Synthesis
DescriptionADX-88178 is a novel potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor in rodent models of anxiety, obsessive compulsive disorder (OCD), fear, depression, and psychosis. ADX88178 dose-dependently reduced the number of buried marbles in the marble burying test and increased open-arm exploration in the elevated plus maze (EPM) test, indicative of anxiolytic-like efficacy.
targetADX88178 is a metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.
2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]- Preparation Products And Raw materials
Raw materials4-(1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-methylthiazol-2-amine-->2-Bromo-4-methylpyrimidine
Tag:2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-(1235318-89-4) Related Product Information