Company Name: |
ShangHai Biochempartner Co.,Ltd
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17754423994 17754423994 |
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2853530910@QQ.com |
Products Intro: |
Product Name:KG5 CAS:877874-85-6 Purity:98% HPLC LCMS Package:100mg;500mg;1g
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Company Name: |
BOC Sciences
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Tel: |
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Email: |
info@bocsci.com |
Products Intro: |
Product Name:KG 5 CAS:877874-85-6 Purity:≥98% by HPLC Remarks:KG 5 is a B-Raf allosteric and PDGFRβ inhibitor. It inhibits FLT3, KIT and c-Raf. It arrests cells in prometaphase and inhibits growth of renal and pancreatic tumors in mice. It also inhibits angiogen
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Product Name: | KG5 | Synonyms: | KG5;2-methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amine;2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine;4-Pyrimidinamine, 2-(methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-;B-Raf,antiangiogenic,KIT,c-Kit,KG5,CD135,Raf kinases,Raf,PDGFR,Cluster of differentiation antigen 135,Platelet-derived growth factor receptor,Fms like tyrosine kinase 3,metastasis,c-Raf,FLT3,PDGFRβ,inhibit,anticancer,phosphorylation,SCFR,Inhibitor,KG 5,CD117,KG-5;2-(Methylthio)-6-(4-(5-((3-(trifluoromethyl)phenyl)amino)-4H-1,2,4-triazol-3-yl)phenoxy)pyrimidin-4-amine | CAS: | 877874-85-6 | MF: | C20H16F3N7OS | MW: | 459.45 | EINECS: | | Product Categories: | | Mol File: | 877874-85-6.mol | ![KG5 Structure](CAS/20180808/GIF/877874-85-6.gif) |
Boiling point | 654.0±65.0 °C(Predicted) | density | 1.54±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | form | Solid | pka | 9.54±0.40(Predicted) | color | White to off-white |
Uses | KG 5 is orally active drug that stabilizes inactive state of PDGFRβ/B-RAF and inhibits tumor angiogenesis. | storage | Store at -20°C |
| KG5 Preparation Products And Raw materials |
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