|
|
| | PF 477736 (HCl) Basic information |
| Product Name: | PF 477736 (HCl) | | Synonyms: | PF 477736 (HCl);(alphaR)-alpha-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]cyclohexaneacetamide hydrochloride | | CAS: | 952238-93-6 | | MF: | C22H26ClN7O2 | | MW: | 455.95 | | EINECS: | | | Product Categories: | | | Mol File: | 952238-93-6.mol |  |
| | PF 477736 (HCl) Chemical Properties |
| | PF 477736 (HCl) Usage And Synthesis |
| Definition | ChEBI: PF-00477736 is a diazepinoindole that is 8-amino-4,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one which is substituted at position 2 by a 1-methylpyrazol-4-yl group and in which the amino group at position 8 has undergone condensation with the carboxy group of (2R)-2-cyclohexylglycine to give the corresponding carboxamide. It is an inhibitor of checkpoint kinase 1 (Chk 1). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an antineoplastic agent. It is an amino acid amide, a member of pyrazoles and a diazepinoindole. |
| | PF 477736 (HCl) Preparation Products And Raw materials |
|