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| | PD089828 Basic information |
| Product Name: | PD089828 | | Synonyms: | PD089828;1-(2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea;Urea, N-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-;EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth factor receptor,ErbB-1,phosphorylation,vascular,antiproliferative,smooth,antimigratory,competitive,Inhibitor,Platelet-derived growth factor receptor,PD-089828,Src,muscle,cells,FGFR,inhibit,Fibroblast growth factor receptor | | CAS: | 179343-17-0 | | MF: | C18H18Cl2N6O | | MW: | 405.28 | | EINECS: | | | Product Categories: | | | Mol File: | 179343-17-0.mol |  |
| | PD089828 Chemical Properties |
| density | 1.416±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 25 mg/ml; Ethanol: 1 mg/ml | | form | A solid | | pka | 9.85±0.43(Predicted) | | color | White to light yellow |
| | PD089828 Usage And Synthesis |
| Uses | PD 089828 is an ATP competitive inhibitor of the growth factor receptor tyrosine kinases FGFR-1, PDGFR-beta and EGFR. |
| | PD089828 Preparation Products And Raw materials |
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